Generated in partnership with Autism Speaks, this model possesses a deletion in exon 8 of MET receptor tyrosine kinase (MET).
Technical Data
Animal Model
Met
Nomenclature
SD- Met tm1sage
Zygosity Genotype
Cryopreserved as heterozygous embryos
Colony Size
Cryopreserved
Research Application
Autism Spectrum Disorders
Synaptic Plasticity
Autoimmune disorders
Research Area
Autism
Characteristics
This model possesses a 17 base pair deletion in exon 8 of MET
This model is provided as a heterozygous knockout; homozygous knockout of MET is not viable
Background Strain: Sprague-Dawley
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