Edit-R crRNA Library
Ensure library specificity - algorithm optimized guide RNA
Arrayed collections of predesigned synthetic crRNA for screening across entire gene families for human and mouse. Use in rapid loss-of-function studies.
Further your functional genomics studies with CRISPR-Cas9 gene editing using Edit-RTM crRNA libraries. Analyze hundreds of genes with multiple target sites per gene. Collections include human druggable and whole genome libraries.
Arrayed library format permits single-well analysis with many phenotypic assays; including high-content assays and other morphological or reporter assays.
Please note that Edit-R synthetic tracrRNATM is required for use with all synthetic crRNA products
Highlights of Edit-RTM crRNA libraries
- Selected by the Edit-RTM algorithm. Highly functional and target sequences specific for robust, reliable gene knockout. Chemically modified for improved nuclease resistance
- For high-confidence phenotypic results, provided as four unique crRNA designs per gene, as individuals or a pooled reagent.
- Conveniently arrayed in 96-or 384-well plates and offered as gene family collections. Echo-qualified 384-well plates are available upon request
- Also available as crRNA cherry-pick libraries; simply upload your own gene list and customize your plate
If you're considering the purchase of a Druggable or Genome crRNA library, learn about how the Genomics Discovery Initiative can support your screening efforts!
Human Druggable is made up of: Proteases, Protein Kinases, Phosphatases, Transcription Factors, Ubiquitin Enzymes, GPCRs, Ion Channels and Drug Targets.
| Human crRNA Libraries | # genes (approximate) | Catalog # (Pool/Set of 4) |
|---|---|---|
| Human Edit-RTM - Cell Cycle Regulation | 169 | GP/GC-003205-xx |
| Human Edit-RTM - Cytokine Receptors | 110 | GP/GC-004005-xx |
| Human Edit-RTM - Deubiquitinating Enzymes | 94 | GP/GC-004705-xx |
| Human Edit-RTM - DNA Damage Response | 240 | GP/GC-006005-xx |
| Human Edit-RTM - Drug Targets | 3686 | GP/GC-004650-xx |
| Human Edit-RTM - Druggable Genome | 8422 | GP/GC-004605-xx |
| Human Edit-RTM - Epigenetics | 835 | GP/GC-006105-xx |
| Human Edit-RTM - G Protein-coupled Receptors | 390 | GP/GC-003605-xx |
| Human Edit-RTM - Genome | 19,127 | GP/GC-005005-xx |
| Human Edit-RTM - Ion channels | 417 | GP/GC-003805-xx |
| Human Edit-RTM - Membrane Trafficking | 140 | GP/GC-005505-xx |
| Human Edit-RTM - Nuclear Receptors | 52 | GP/GC-003405-xx |
| Human Edit-RTM - Phosphatases | 248 | GP/GC-003705-xx |
| Human Edit-RTM - Proteases | 527 | GP/GC-005105-xx |
| Human Edit-RTM - Protein Kinases | 746 | GP/GC-003505-xx |
| Human Edit-RTM - Transcription Factors | 1580 | GP/GC-005805-xx |
| Human Edit-RTM - Tyrosine Kinases | 90 | GP/GC-003105-xx |
| Human Edit-RTM - Ubiquitin Enzymes | 738 | GP/GC-006205-xx |
| Mouse crRNA Libraries | # genes (approximate) | Catalog # (Pool/Set of 4) |
| Mouse Edit-RTM - Cell Cycle Regulation | 105 | GP/GC-013200-xx |
| Mouse Edit-RTM - Cytokine Receptors | 139 | GP/GC-014000-xx |
| Mouse Edit-RTM - Deubiquitinating Enzymes | 100 | GP/GC-014700-xx |
| Mouse Edit-RTM - Epigenetics | 724 | GP/GC-016100-xx |
| Mouse Edit-RTM - GProtein-coupled Receptors | 515 | GP/GC-013600-xx |
| Mouse Edit-RTM - Ion Channels | 340 | GP/GC-013800-xx |
| Mouse Edit-RTM - Membrane Trafficking | 113 | GP/GC-015505-xx |
| Mouse Edit-RTM - Nuclear Receptors | 46 | GP/GC-013400-xx |
| Mouse Edit-RTM - Phosphatases | 273 | GP/GC-013700-xx |
| Mouse Edit-RTM - Proteases | 599 | GP/GC-015100-xx |
| Mouse Edit-RTM - Protein Kinases | 774 | GP/GC-013500-xx |
| Mouse Edit-RTM - Transcription Factors | 1419 | GP/GC-015800-xx |
| Mouse Edit-R - Tyrosine Kinases | 92 | GP/GC-013105-xx |
| Mouse Edit-RTM - Ubiquitin Enzymes | 752 | GP/GC-016200-xx |
