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Custom siRNA

Easy online ordering of standard, Dharmacon enhanced, and modified siRNAs. Ability to incorporate mismatches and internal modifications except for positions where restricted by Dharmacon patented modifications do not allow for changes in base content.

All oligos made by Dharmacon are verified for quality using mass spectrometry. This data is available on request for a fee. Additionally, we can provide UHPLC data on request as an additional service. Contact Scientific Support for more information.

Revvity is committed to biosecurity and the responsible synthesis of oligonucleotides. For more information on how the Dharmacon Reagents are screened and how we adhere to the US Framework for Nucleic Acid Synthesis, please visit our Synthetic Oligonucleotide Sequence Screening page.

Step One

Select Options in order to determine available scale

* The nmol size is the guaranteed amount of material you will receive for an unmodified siRNA. Modifications will decrease this yield. For any questions, please contact us

Step Two

5'
3'
5'
3'
5'
3'
5'
3'
Sense length with overhangs:

Messages:

Step 3

Select bases with left mouse button, choose base modifications with right mouse button. Multiple cells may be selected by dragging the mouse while holding left mouse button down or by pressing Ctrl-key while clicking left mouse button.

See all Bases and Modifications for custom siRNA synthesis

Click to change
5'
3'
Sense
3'
Antisense
5'
Metric
Sense
Antisense
Duplex
Max. calculated Yield (in mg)**
GC:
 
 
N/A
Mol. Wt.
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  mg
e260
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**GC%, MW, e260, and yield stated are estimates for unmodified siRNA. Modifications will affect these values and may decrease actual yield. Please refer to the product form delivered with the siRNA for precise values. For any questions, please contact us.
Pricing
Total Price:  
Days to Manufacture: