Our website has a fresh new "look"
We've updated our site with modern design and easier navigation, but you'll still find the same quality Dharmacon™ reagents and Mimix™ reference standards that you love.
Dharmacon reagents | Infinite possibilities for genomic perturbation.
CRISPR, RNAi & Custom oligo synthesis. Genome-scale tools for gene knockout, knock-in, knockdown, activation, and more. 30+ years of proven expertise.
Mimix reference standards
Cell line-derived reference materials. Mimic patient samples. FFPE, cfDNA, gDNA, fcDNA formats. Confidently verify your molecular oncology workflows.
We've updated our site with modern design and easier navigation, but you'll still find the same quality Dharmacon™ reagents and Mimix™ reference standards that you love.
内在性遺伝子を改変した細胞株の解析は、遺伝子または遺伝子変異が表現型に与える影響の明確な解釈を可能にします。
目的遺伝子以外は遺伝的に同質(アイソジェニック)な親細胞株とのペアで提供します。親細胞株は、実験のコントロールとなり、他の要因に影響されずに目的遺伝子の役割を研究することを可能にします。
私共のノックインモデルでは、次のようなより複雑な遺伝子改変細胞株製品もご用意しています。
Our catalog of cell lines has become a gold-standard resource
in antibody validation, cancer research, and early drug-discovery research. Horizon was recently recognized by CiteAb as the Cell Line Supplier to Watch in Cancer Research for 2024. Read more about the CiteAb award.
Horizon Discoveryの細胞株をご購入の際は、細胞株の限定使用ラベルライセンス(LULL: LIMITED USE LABEL LICENSE AGREEMENT)へのご同意が必要です。
しかしながら、HAP1細胞およびがん関連細胞のカタログ細胞株の性能に満足できない場合は、テクニカルサポートまでご連絡ください。当社の販売条件に詳述されているように、問題を解決するためにお客様と熱心に協力します。
All cell line engineering projects are subject to our Terms & Conditions and our Limited Use Label License.
Products that have utilized CRISPR Cas9 systems and methodologies to knock-in a gene, and their use, may be the subject of one or more of the following patents and applications controlled by Sigma-Aldrich Co. LLC (SIGMA): Patent applications and issued patents that entered their respective National Stage from PCT International Pub. No. WO 2014/089290, including, but not limited to, the following, and substitutions, divisions, continuations, continuations-in-part, reissues, re-examinations, and extensions thereof: Australia Patent Nos. 2013355214; 2017204031; and 2018229489; Canada Patent Nos. 2,891,347 and 2,977,152; China Patent No. CN105142669; European Patent Nos. EP 2 928 496 B1; EP 3 138 910 B1, 3 138 911 B1, EP 3 138 912 B1, EP 3 360 964 B1, EP 3 363 902 B1; Israel Patent No. IL238856; Singapore Patent No. 11201503824S; South Korea Patent Nos. 10-1844123 and 10-2006880; and U.S. Patent Nos. 10,731,181 and 10,745,716; and U.S. Application Serial Nos. 15/188,927; 15/188,931; and 15/456,204 (the “Patent Rights”).