Whether you're conducting single-gene studies or genome-wide screens, Revvity provides the most comprehensive portfolio of functional genomic tools available. Our Dharmacon™ solutions span the entire research spectrum—DNA, RNA, protein, and even cells lines—giving you precise control over gene modulation and editing to accelerate your path from discovery to therapeutic breakthrough.
Advanced genomic solutions, unmatched expertise
Ready to advance your research? Explore our latest innovations designed to tackle today's most complex genomic challenges.
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Strict-R is a novel dual-regulated inducible CRISPR system where transcription of the transgene is repressed and the transgene protein is unstable in the absence of small molecule inducers. This dual control dramatically reduces background activity while maintaining full activity, ensuring stringent control of ON and OFF state. |
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Purified ready-to-use Cas9 protein with a new and improved NLS composition enabling more efficient nuclear delivery for rapid RNP workflows.
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Our Pin-point™ base editing design tool makes it simple to create base editing sgRNAs that deliver reliable, high-efficiency gene knockouts.
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All Edit-R human sgRNA designs have been updated to the latest RefSeq in 2025 providing the most specific and genomically relevant guides for protein knockout. This update allows the Edit-R algorithm to target the latest genome annotations providing you with the best solution for your research. |
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LentiBOOST transduction enhancer can increase successful viral transduction in challenging to transduce cells or complex cellular engineering work, while preserving cell viability and minimizing the amount of viral particles required for your experiment. It's been tested with Dharmacon lentiviral reagents and is now available on our website. |
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Our newest pre-engineered and ready-to-ship HAP1 cell lines for a selection of popular genes, including SMAD5, KLF6, ATM, SYK, NPM1, BRCA1, PARP1, RPTOR, BCL2L1, SKP2, PUDP, KCTD7, DNAJC5, CTSF, and KLHL22.
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NGS library prep kits offering complete screening-to-NGS solutions for all CRISPR lentiviral sgRNA pooled libraries.Learn more Lentiviral sgRNA pooled librariesAll-in-one lentiviral sgRNA whole genome pooled libraryCRISPRa All-in-one Lentiviral sgRNA Whole Genome Pooled LibraryCRISPRi All-in-one Lentiviral sgRNA Whole Genome Pooled Library |
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Cutting controls target safe harbor (AAVS1 and Rosa26) regions for genomic cuts without phenotypic changes. Validated for mismatch detection assays, they're perfect for confirming Cas9 activity in screening applications without functional consequences.
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New validated synthetic controls targeting the constant regions of the T-cell receptor for TRAC, TRBC, TRDC and available for both sgRNA and crRNA formats.
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