Validated positive controls and non-targeting negative controls designed for use with next-generation ON-TARGETplus 2.0 siRNAs. Featuring proprietary On-TARGETplus synthetic modifications for superior specificity and minimized off-target effects. Available as pooled or single siRNAs.
ON-TARGETplus 2.0 control siRNAs integrate the legacy ON-TARGETplus synthetic modification pattern, delivering improved specificity, reduced seed-based off-targeting, and enhanced consistency across experiments. These controls are recommended for any siRNA workflow utilizing ON-TARGETplus 2.0 reagents.
Our expanded panel of non-targeting negative controls enables evaluation of potential non-specific responses, helping you identify the most appropriate negative control for your cell type and assay conditions. Pooled siRNA controls are recommended when additional off-target reduction is desired and are ideal for use alongside ON-TARGETplus 2.0 pooled siRNA reagents.
Select a species-specific positive control to efficiently silence a robustly expressed housekeeping gene in your experimental system, ensuring confident confirmation of transfection efficiency and pathway engagement.
| ON-TARGETplus 2.0 Positive Control Reagents | Species | Catalog Number |
|---|---|---|
| ON-TARGETplus 2.0 Cyclophilin B Control siRNA | Human | D2-001820-01 |
| Mouse | D2-001820-02 | |
| Rat | D2-001820-03 | |
| ON-TARGETplus 2.0 Cyclophilin B Control Pool | Human | D2-001820-10 |
| Mouse | D2-001820-20 | |
| Rat | D2-001820-30 | |
| ON-TARGETplus 2.0 GAPD Control siRNA | Human | D2-001830-01 |
| Mouse | D2-001830-02 | |
| ON-TARGETplus 2.0 GAPD Control Pool | Human | D2-001830-10 |
| Mouse | D2-001830-20 | |
| ON-TARGETplus 2.0 Negative Control Reagents | Species | Catalog Number |
| ON-TARGETplus 2.0 Non-targeting siRNAs | Human, Mouse, Rat | D2-001810-0X |
| ON-TARGETplus 2.0 Non-targeting Pool | Human, Mouse, Rat | D2-001810-10 |