Mimix OncoSpan Reference Control Panel
Bring comprehensive controls to your cancer assays
Mimix™ OncoSpan™ is one of the world's most variant-rich oncology reference material. Benefit from a companion batch-specific NGS data set and onco-relevant variants across 152 key genes important to cancer screening and monitoring.
Mimix OncoSpan controls
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Mimix OncoSpan cfDNA reference standard
Cell-free DNA in buffer or alternate plasma for use in liquid biopsies. -
Mimix OncoSpan FFPE reference standard
Cells embedded in FFPE slides for use in extraction and assay control. -
Mimix OncoSpan gDNA reference standard
High quality genomic DNA for use in assay control.
Key Features
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Highly multiplexed reference control panel containing over 370 variants across 152 oncogenes, including >27 indels
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Cell line-derived control material commutable to patient samples
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Develop, troubleshoot and assess bioinformatics performance with a companion high coverage, batch specific in silico NGS data set
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Available in cell-free DNA, FFPE curls, and genomic DNA formats
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Range of allele frequencies supports rapid determination of LOD in your research assay and sensitivities
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Demonstrated repeatability with an R2 correlation coefficient in NGS ranging from 0.95 to 0.97 across Mimix OncoSpan formats
Renewable and highly characterized
Take advantage of a renewable and highly characterized reference control material. Well suited to large NGS panel applications, Mimix™ OncoSpan™ oncology reference panel helps to provide you with consistency from research assay development to routine monitoring.
Mimix OncoSpan applications include:
- Cancer research assay development
- Routine monitoring of research assay performance and data analysis
- Large NGS panels
Utilize Mimix OncoSpan controls to monitor your assays.
- Improve subject selection for research studies
- Develop cancer detection methods
- Assess therapeutic efficacy
Mimix OncoSpan publications
Read these research articles citing the use of Mimix OncoSpan reference standards.
- Validation of a pan-cancer targeted next generation sequencing panel in New Zealand | New Zealand Journal of Medical Laboratory Science
- Enabling variant calling in challenging FFPE samples by coupling a novel library preparation chemistry with exome sequencing | Journal of Clinical Oncology
- Moving towards a local testing solution for undetermined thyroid fine-needle aspirates: validation of a novel custom DNA-based NGS panel | Journal of Clinical Pathology
- Performance Analysis of Three Bioinformatic Variant Callers Using a Somatic Reference Standard | Children's Mercy Kansas City
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For research use only. Not for use in diagnostic procedures.