Reference standards for confident assay validation

Consistency from assay development to routine monitoring


Improve your assay development, validation and routine monitoring with cell-line derived reference standards. Patient-like performance and batch-to-batch consistency eliminates variability in your quality control program while saving time and cost.
Find reliable controls suitable for your sample type and analysis technique.

Create your own reference standard

Use our new online tool to create your own reference material in 5 simple steps!

  1. Choose the format
  2. Select up to 4 variants 
  3. Select allele frequency
  4. Choose the amount and/or concentration
  5. Generate your quote

OncoSpan - the largest oncology reference standard

Browse the range of OncoSpan reference standards:

  • Contains over 370 variants across 152 oncogenes
  • Available in gDNA, FFPE or cell-free DNA 
  • Cell line-derived to closely mimic patient samples
  • Ideal for end-to-end workflow validation and routine monitoring

Latest products

Prostate Cancer Panel cfDNA Reference Standard

  • Horizon's latest cell-free DNA panel contains 15variants across 9 genes relevant to prostate cancer
  • Manufactured under ISO:13485
  • Negative control also available 



Horizon partner with MDIC

Read about our collaboration with MDIC's SRS Initiative and the ten new materials available early 2024

Horizon shines in FNIH study

Download this new literature review that highlights Horizon's performance in an FNIH study on ctDNA assays

Analysis techniques

Controls for sequencing and amplification-based technologies
  • Next Generation Sequencing (NGS)
  • Large panel NGS 
  • Sanger and qPCR


Standards closely mimicking patient samples
  • cell-free DNA
  • genomic DNA
  • FFPE sections

Sample types

Reference material suitable for any workflow
  • Liquid biopsy
  • Solid tumor analysis