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RNA interference (RNAi) reagents for Gene Silencing studies

Designed for researchers performing target validation, pathway analysis, and screening experiments.

Explore RNA interference (RNAi) reagents for transient and stable gene silencing. Access siRNA, shRNA, and microRNA mimics and inhibitor reagents pre-designed using validated algorithmic approaches to support target identification, mechanism-of-action studies, hit validation, and functional genomics research. Available as tubes or libraries of individual or pools of reagents.

siRNA, shRNA, microRNA mimics & inhibitors, validated controls
Solutions for transient and stable knockdown
Genome-scale screening libraries
Millions of gene-specific designs across species

Reagents

Controls, additional reagents, and libraries

Explore RNAi application areas

siRNA applications

siRNA is the go-to tool for targeted gene silencing - but how does it work, and is it right for your research? Explore the science behind siRNA, how it's delivered into cells, and how it's being used to unlock insights into cancer, HIV, and more.

shRNA applications

For research requiring long-term or stable gene silencing, shRNA offers a powerful DNA-based approach. Discover how DNA-encoded shRNA vectors and viral delivery systems enable sustained knockdown, even in hard-to-transfect cells, and how they’re powering large-scale genome-wide screens across a broad range of disease research areas.

microRNA applications

microRNAs are unique among RNAi tools in their ability to regulate hundreds of genes simultaneously, making them powerful levers for understanding complex biological processes. Understand the tools that mimic or inhibit endogenous microRNA function.

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