Engineered cell models

Work in biologically and clinically relevant cell backgrounds


Horizon combines innovative technology with deep practical expertise to provide unrivaled cell line engineering solutions. Our dedicated team has a proven record of delivering quality and timely results, with over a decade of editing experience in hundreds of cell lines – including many challenging-to-edit lines such as iPSCs and primary cells.
Our flexible approach offers solutions to meet your project timeline and budget. From our extensive catalog of 7,500+ "ready-to-go"cell lines that ship immediately, to our custom cell line engineering services, we are here to help!

Cell line engineering with Horizon

Design your own cell line

Get an instant quote and timeline for your next cell line engineering project.

Simply enter your project requirements into our interactive web tool to get started.

Ready-to-go cell lines

Start experimenting immediately!

Find 1000's of validated knockout models, point mutations in cancer-relevant cell models, and Cas9 and dCas9-VPR expressing stable cell lines. Ready to ship today.

Keep your team focused on the big picture

Outsource your cell line engineering or screening projects with Horizon and benefit from our years of expertise and lab automation equipment.

Validate data using knockout cell models

See 5 ways knockout cell lines can be used to validate your research and extend your investigations – from gene rescue to replication of disease mutations.

Recent HAP1 publications

View a list of peer-reviewed publications using our gene knockout HAP1 cell line models.