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Engineered cell models

Work in biologically and clinically relevant cell backgrounds

Horizon combines innovative technology with deep practical expertise to provide unrivaled cell line engineering solutions. Our dedicated team has a proven record of delivering quality and timely results, with over a decade of editing experience in hundreds of cell lines – including many challenging-to-edit lines such as iPSCs and primary cells.

Our flexible approach offers solutions to meet your project timeline and budget. From our extensive catalog of 7,500+ "ready-to-go"cell lines that ship immediately, to our custom cell line engineering services, we are here to help!

Cell line engineering with Horizon

Design your own cell line

Get an instant quote and timeline for your cell line engineering project in less than one minute. Simply enter your project requirements to get started!

Ready-to-go cell lines

Start experimenting immediately — Find 1000's of validated knockout models, point mutations in cancer-relevant cell models, and Cas9 and dCas9-VPR expressing stable cell lines.

Custom engineering service

Learn more about our custom cell line engineering capabilities and service offerings — including work in difficult-to-edit lines, primary cells and iPSCs. 

Keep your R&D team focused on the big picture

Outsource your cell line engineering or screening projects with Horizon and benefit from our years of expertise and lab automation equipment.

5 ways to validate your research using knockout cell models

Read more about how knockout cell lines, either together with gene rescue and replication of disease mutations, or as an independent cell model, can be used to validate your research and extend your investigations.

Recent HAP1 publications

View a list of peer-reviewed publications using our gene knockout HAP1 cell line models.