CRISPRmod CRISPRa dCas9-VPR Stable Cell Lines
Streamline CRISPR activation experiments with stably expressing dCas9-VPR cell lines
Choose from a range of common cell line backgrounds, then simply deliver CRISPRa guide RNA for straightforward gene activation.
CRISPR activation ready cells
- Generated using Horizon's own CRISPRa dCas9-VPR vectors with a Blasticidin resistance selection marker.
- QC validated to ensure stable expression and functionality of dCas9-VPR endonuclease.
- Cells are provided in a pooled format of >1 million cells per vial.
Ideal for use with other Horizon products
For individual gene activation experiments and gain-of-function studies use CRISPRa synthetic crRNA or lentiviral sgRNA. For screening projects, see our predefined gene family, druggable or whole genome CRISPRa synthetic crRNA screening libraries or use our Cherry Pick Custom Library Tool to build your own CRISPRa library.
Proven models
Our catalog of cell lines has become a gold-standard resource
in antibody validation, cancer research, and early drug-discovery research. Horizon was recently recognized by CiteAb as the Cell Line Supplier to Watch in Cancer Research for 2024. Read more about the CiteAb award.
Limited use agreement
All cell lines engineered by Horizon Discovery are purchased under the terms of our Limited Use Label License.
