Mimix™ Colorectal Cancer Panel Negative Control, ctDNA Reference Standard

The Colorectal Cancer ctDNA Panel reference standard negative control is well characterized, cell line-derived control material manufactured under ISO 9001:2015 and ISO 13485:2016 that is tested negative for 10 variants across 10 genes clinically relevant to colorectal cancers.

Clearance sale: Discounted pricing on selected cfDNA inventory. Limited availability.*

*This pricing promotion is only valid on selected products and while stocks last. Not valid in Italy and China. The promotion cannot be combined with any other promotions, discounts, or offers. Conditions of the promotions may change, and Revvity may void, change, cancel, suspend, or amend this promotion without notice.

本製品は研究用です。診断にはご使用いただけません。

The Colorectal Cancer ctDNA Panel reference standard negative control is thoroughly tested and confirmed to be negative for all the 10 clinically relevant mutations using ddPCR. This cell line-derived panel is manufactured under ISO 9001:2015 and ISO 13485:2016. This panel can be used as a negative control or to dilute the allele frequency of the CRC ctDNA panel reference standard - HD842, further enabling assessment of MRD.

Technical data

Format: ctDNA

Genes covered: ABL1, ALK, AKT1, APC, BRAF, PIK3CA, KRAS, NRAS, PTEN, TP53

Allelic frequencies: 0.00%

Buffer: Tris-EDTA (10mM Tris-HCl, 1mM EDTA), pH 8.0

Product information

Fragment size: 160 bp

Unit size: 350 ng per vial

Concentration: 20 ng/µl

Verified mutations:

Gene	DNA sequence change	Amino acid change
ABL1	c.1001C>T	p.T315I
ALK	c.3522C>A	p.F1174L
AKT1	c.49G>A	p.E17K
APC	c.8140C>T	p.R2714C
BRAF	c.1799T>A	p.V600E
PIK3CA	c.1624G>A	p.E542K
KRAS	c.35G>A	p.G12D
NRAS	c.181C>A	p.Q61K
PTEN	c.388C>T	p.R130*
TP53	c.722C>T	p.S241F

General information

Storage: 4°C

Expiration: See all product shelf life information

Quality control

Fragmentation size: D1000 DNA ScreenTape assay

Allelic frequency: Droplet Digital™ PCR

Quantification: Qubit® dsDNA BR assay (Invitrogen)

Intended use: For assay developers and molecular diagnostic labs for routine performance monitoring of molecular biology assays. Research use only. Not for diagnostic procedures.