Discovery Horizon's CRISPRmod systems (CRISPR interference and CRISPR activation) for translational modulation of target gene expression. Learn how each system works, when to use CRISPRi for down-regulation or CRISPRa for up-regulation of endogenous gene expression, and how to design successful experiments using these reagents.
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View the new poster presentation video demonstrating the creation of knockins with the EditR CRISPRC
Lipid-mediated transfection of CRISPR-Cas9 and single-strand DNA oligos for homology-directed repair
Design rules improve the efficiency, specificity and functionality of gene knockout
An article in the Journal of Biotechnology on the applications of chemically synthesized guide RNAs
A custom knock-in kit designed just for you
Edit-R™ inducible lentiviral Cas9 nuclease gives you increased flexibility in your experiment
Applications of targeted CRISPR-Cas9 labeling with potential clinical diagnostic implications
Improved functionality and specificity of genome editing experiments that only requires a gene search!
Avoid confusion! DNA cleavage and gene editing are not the same.
Between choosing the right reagents and detecting changes at the genomic level, many factors need to be considered to create a well-designed CRISPR-Cas9 experiment.