Between choosing the right reagents and detecting changes at the genomic level, many factors need to be considered to create a well-designed CRISPR-Cas9 experiment.
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A gene editing revolution is underway in plant systems
When you need to knockout a gene next week, not next month
Use the HDR Donor Designer to generate a custom ssDNA oligo template for your knock-in experiment!
Ensure your percent gene editing calculations are correct
Use CRISPR with Confidence! Reagents you can trust for your gene editing experiments.
When to express Cas9 from the same vector as your sgRNA
Synthetic crRNA and tracrRNA can be used in high-throughput screening applications
While genome engineering is widely ascribed with the capacity to knock out genes of interest, new adaptations of these same molecular building-blocks are reshaping the way researchers think about the opposite: overexpression experimen
Dharmacon™ Edit-R™ has been featured in over 20 peer-reviewed publications since 2015