Yeast Reagents
Our yeast resources allow researchers to interrogate the yeast genome with precision, from tagged ORF collections and knockout or mutant strains to protein-protein interaction tools and screening libraries.
Whether you're mapping genetic pathways, validating drug targets, or exploring essential gene function, our curated collections provide the flexibility and quality needed for reproducible, high-confidence results.
Tagged ORFs
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Yeast ORFs
Individual gateway-adapted yeast ORFs from the Yeast ORF collection for functional studies. -
Yeast ORF collection
Gateway-adapted yeast ORFs cloned into expression plasmids. ORFs can be expressed as fusion proteins or moved to other vectors. -
Yeast YFP Fusion Kinase collection
Contains a number of kinase genes that have been cloned with a C-terminal YFP tag and promoter region into a Gateway-entry vector. -
Yeast TAP-tagged ORFs
Individual yeast ORFs with TAP tags for protein interaction and purification studies. -
Yeast TAP-tagged ORF collection
Yeast TAP-Tagged ORF library enables dual-affinity purification and selection of yeast proteome and associated components. -
Molecular Barcoded Yeast (MoBY) ORF collection
Identifies S. cerevisiae genes conferring drug resistance when mutated - a tool for finding resistant mutations in yeast. -
Yeast GST-tagged ORFs
Individual yeast ORFs with GST tags for protein expression and purification applications. -
Yeast GST-tagged ORF collection
More than 5,000 yeast strains that each overexpresses a different yeast open reading frame (ORF) when induced with galactose. -
Yeast HA Tag collection
Mutagenized yeast strains with triple hemagglutinin (HA) epitope tags, useful for immunolocalization, immunoprecipitation, and analysis of binding sites. -
Yeast Barcoder collection
A set of approximately 1,400 donor strains with unique DNA sequence tags (barcodes) that can be systematically transferred to any S. cerevisiae collection.
Knockout Strains
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Yeast knockouts
Individual yeast knockout mutants for gene function and phenotypic analysis. -
Yeast knockout collection
Over 6,000 gene-disruption mutants as a unique tool for the functional analysis of the yeast genome. -
Yeast tet-promoters Hughes (yTHC)
Individual yeast tet-promoter strains from the Hughes Collection for conditional gene expression. -
Yeast Tet-promoters Hughes collection (yTHC)
800 essential yeast genes under tetracycline-regulated promoter control for experimental gene regulation. -
Yeast parental strains
Parental yeast strains compatible with the Yeast Knockout and other yeast collections.
Protein-Protein Interaction Collections
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Yeast Protein Interactome collection
The Yeast Protein Interactome Collection allows for genome-wide in vivo screening of protein-protein interactions (PPI) in Saccharomyces cerevisiae. -
Yeast Cross and Capture System
The Yeast Cross and Capture system is designed to examine protein-protein interactions and protein modifications using 6xHIS and VSV tagged haploid yeast strains.
Mutant Strains and Screening Collections
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Yeast Insertional Mutant
Individual yeast insertional mutants for gene disruption and functional genomics research. -
Yeast Insertional Mutant collection
The Yeast Insertional Mutant collection contains a set of over 3,600 gene disruption mutants for phenotypic analysis. -
Yeast Synthetic Histone collection
Systematic mutations have been engineered into the Yeast Synthetic Histone H3 and H4 mutants in order to elucidate nucleosome functionality. -
Yeast Genomic Tiling collection
Designed to facilitate comprehensive overexpression screens, the yeast (Saccharomyces cerevisiae) genome in a 2 micron-based LEU2 vector. -
Yeast DAmP
Individual Yeast Decreased Abundance by mRNA Perturbation (DAmP). -
Yeast DAmP collection
Reduce mRNA levels of essential yeast genes by four- to ten-fold with the Decreased Abundance by mRNA Perturbation (DAmP) Yeast Library.
