HAP1 knockout cell lines

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HAP1 Parental Cell Lines available

USP16 ( Human )

Entrez Gene 10600 entrezgene 10600
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ubiquitin specific peptidase 16

Alias

UBP-M | UBPM

This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].