miRIDIAN microRNA Mimic Negative Controls are ideal for optimizing conditions for relevant, well-controlled microRNA modulation experiments. Both positive and negative control molecules are provided for gain-of-function microRNA studies.
- Based on cel-miR-239b, mature sequence:
- Cel-miR-239b confirmed to have minimal sequence identity with miRNAs in human, mouse, and rat
- Identical design and modifications as miRIDIAN microRNA Mimics
- No identifiable effects on tested miRNA function (see Figure 1, Supporting Data)
- Non-targeting mimics for use as controls in miRNA mimic experiments
- Distinguish between specific mimic activity and background effects
Submit an online quote request for larger quantities of RNAi Controls or siRNA Libraries.
miRIDIAN microRNA Mimic Negative Controls have no apparent effect on tested miRNA function
Figure 1. | Effects of miRIDIAN microRNA Mimic Negative Controls on the function of three human miRNAs were assayed at 24 hours after transfection of 10 nM mimic or negative control in HeLa cells using a dual luciferase reporter system.