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Custom Reference Standards for Oncology Assays

Create your own Mimix reference material.

With our made-to-order and custom options, you can generate your own Mimix™ reference material to bring patient-like performance tailored to your assay development, verification, and routine QC.

Molecular oncology assays require precise, reliable reference materials that maintain genomic complexity and mimic patient samples.

Whether you’re developing a new assay or monitoring routine workflows, made-to-order Mimix™ reference standards complement our off-the-shelf products by giving you full control over variants, allele frequencies, and formats.

Choose from a wide range of product formats and variant types, including SNVs, CNVs, INDELs, and fusions.
Select allele frequencies as low as 0.1%
Enhance your analysis with optional whole-genome or whole-exome sequencing for deeper insights into assay performance.

Why choose made-to-order Mimix controls

With our made-to-order Mimix reference standards, you can benefit from:

Human cell-line derived controls that mimic patient material
Quality products developed and manufactured under ISO 13485:2016 and ISO 9001:2015
Rigorously QC tested products so you can have confidence in your results
Compatibility across a range of platforms, including Next Generation Sequencing, Droplet-Digital PCR, Real-Time PCR and Sanger sequencing

Common applications for made-to-order and custom oncology control material

Here are some typical applications for our made-to-order and custom reference standards:

Molecular oncology assay kit controls
NGS assay development and optimization for less common genes
Sensitivity and limit of detection studies with low AF
Cancer genomic or disease-specific assay verification
Liquid biopsy assay development

How to request a made-to-order reference standard

To get started, you will need to provide our team with some information about your requirements:

Format, such as gDNA, FFPE, cfDNA in buffer, cfDNA in synthetic matrix, fcDNA
Gene symbol(s) (e.g. BRCA1, TP53) and/or specific variant(s) of interest, using standard nomenclature (e.g. HGVS)
Allele frequency for each variant - from as low as 0.1%
The quantity of material required

Using this information, our team will contact you to discuss your requirements and generate a custom quote for you.

Advanced customization services

If you need reference material with more advanced customization, such as methylation and enzymatic fragmentation, please contact our specialist team to discuss your requirements.

Frequently asked questions

What formats are available for made-to-order Mimix reference standards?

Format options for our made-to-order Mimix reference standards include gDNA, FFPE, cfDNA in buffer, cfDNA in synthetic matrix, and fcDNA.
What is the minimum allele frequency you can provide?

Our made-to-order Mimix reference standards can be made with allele frequencies as low as 0.1%.
Are there minimum order quantities?

Minimum order quantities may apply depending on the sample type or level of customization requested. However, there are no fixed or universal minimums.

Please specify the amount of material you require, including units (e.g. ng, µg, mL, number of samples) in your request.
What is the typical turnaround time?

Once you have confirmed your requirements and placed the order, our made-to-order Mimix controls are typically shipped to you in around 4-12 weeks. This timeframe depends on your specific requirements so may be shorter or longer than 4-12 weeks. For example, turnaround times for gDNA/cfDNA formats are typically shorter than FFPE DNA formats.

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