Mouse ON-TARGETplus siRNA Library - Phosphatases
siRNA designed and modified for greater specificity
An arrayed collection of siRNA reagents for RNAi screening, targeting mouse phosphatases. ON-TARGETplus siRNA is guaranteed to silence and is modified to reduce off-targets for fewer false positives.
With the Mouse ON-TARGETplus Phosphatases siRNA Library, researchers receive siRNAs targeting enzymes with known or predicted phosphatase activity. Phosphatases play key roles in many biological processes, including cell-cycle progression, replication, transcription, and RNA processing. Cells depend on phosphatases to maintain tight control over the activity of several metabolic enzymes and signal transducing factors.
The ON-TARGETplus siRNA designs and modifications reduce off-target effects while maintaining high-silencing potency for high-confidence screening results.
Highlights
- Patented dual-strand ON-TARGETplus modification pattern on all siRNAs to reduce off-targets
- Sense strand is modified to prevent interaction with RISC and favor antisense strand uptake
- Antisense strand seed region is modified to destabilize off-target activity and enhance target specificity
- Available as SMARTpool siRNA reagents or a Set of 4 siRNAs in 96-well plates
- Guaranteed target gene knockdown (see Specifications tab)
Gene Targets
For a complete list of target genes in this siRNA Library, please contact Scientific Support.
