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Pin-point™ Base Editing Reagents

All Dharmacon™ Reagents

Explore All Dharmacon™ Reagents New and updated products

Gene Editing

Explore Gene Editing CRISPR guide RNA Cas9 nucleases Controls Custom guide RNA Knock-in templates Cherry-pick library tool - clones Cherry-pick library tool - synthetic CRISPR libraries

Gene Knockdown

Explore Gene Knockdown siRNA shRNA microRNA Controls lncRNA Custom siRNA design Cherry-pick library tool - synthetic Cherry-pick library tool - clones RNAi libraries

Gene Expression

Explore Gene Expression CRISPRa cDNA & ORFs

CRISPR Modulation

Explore CRISPR Modulation CRISPRi CRISPRa CRISPR modulation libraries dCas9 stable cell lines Controls

Reference Standards

Explore Reference Standards Create your own reference standard Mimix Geni standards Oncospan Analysis technique Sample type Format Reference standards for assay developers

Libraries

Explore Libraries CRISPR libraries RNAi libraries Cherry-pick library tool - clones Cherry-pick library tool - synthetic

Engineered Cell Models

Explore Engineered Cell Models Knockout cell lines Double knockout cell lines Cancer related cell lines Cas9 stable cell lines dCas9 stable cell lines

Custom Oligonucleotides

Explore Custom Oligonucleotides Single-strand RNA synthesis Custom siRNA Custom antisense oligonucleotides Custom DNA Custom microRNA

Non-mammalian research

Transfection & Ancillary Reagents

Bioproduction Cell Lines

Explore Bioproduction Cell Lines CHOSOURCE™ GS KO cell line CHOSOURCE™ ADCC+ cell line CHOSOURCE™ TnT transposon technology
CRISPR guide RNA
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Dharmacon Edit-R Protein Hybrid NLS

Functional Genomic Screening

Explore Functional Genomic Screening Arrayed screens Pooled screens CRISPR screens RNAi screens Single-cell CRISPR screens Immune cell screens Pin-point base editing

Immune Cell Screening

Explore Immune Cell Screening CRISPR immune cell screens Custom immune cell screens

Compound screening assays

iTreg Polarization assay iTreg Suppression assay T Cell Activation assay Mixed Lymphocyte Reaction assay

Cell Panel Screening

Explore Cell Panel Screening 2D OncoSignature 2D OncoSignature Long-term assay 3D OncoSignature Custom screens

Cell Line Engineering

Explore Cell Line Engineering Knockout Knock-in Bioproduction cell engineering

Custom Libraries

Custom Oligonucleotides

Contract Research Services

Pin-point™ Base Editing Services

Explore Pin-point™ Base Editing Services Pin-point™ Platform Cell Line Engineering Services Pin-point™ Pooled Tiled Screen Services

Custom Reference Standards

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Gene Editing

Explore Gene Editing Synthetic sgRNA for CRISPR-Cas9 experiments CRISPR-Cas9 guide RNA algorithm Inducible lentiviral Cas9 nuclease Multiplex CRISPR-Cas9 knockout All-in-one CRISPR knockout Synthetic lethality

CRISPRmod

Explore CRISPRmod CRISPR interference CRISPR activation CRISPRa MS2 tracrRNA All-in-one CRISPR modulation

RNA Interference

Explore RNA Interference siRNA Self-delivering siRNA shRNA microRNA Noncoding RNA

Engineered Cell Lines

Explore Engineered Cell Lines Antibody validation Autophagy pathway Bromodomain containing proteins Caspases Deubiquinating enzymes (DUBs) DNA damage pathways Drug targets Epigenetics Histone acetylation Kinase inhibition mTOR pathway Parkinson's disease Phosphoinositide function Phospholipases Primary and stem cells Rab GTPases Serine threonine phosphatase Sialylation pathway