HAP1 knockout cell lines

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HAP1 Parental Cell Lines available

SUFU ( Human )

Entrez Gene 51684 entrezgene 51684
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SUFU negative regulator of hedgehog signaling

Alias

PRO1280 | SUFUH | SUFUXL

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].