Bases and modifications for custom synthesis

We offer a wide array of oligonucleotide modifications for your specific custom synthesis applications. Scroll through RNA type and position below for online ordering availability.

NOTE: Not all modifications are available through online ordering tool. For assistance please contact Technical support.

Filter by:

  • siRNA
  • ssRNA
  • ssRNA-3'
  • ssRNA-Internal
  • ssRNA-5'
  • miRNA
  • SHOW ALL

Showing modifications available for:

  • siRNA
  • ssRNA
  • ssRNA-3'
  • ssRNA-Internal
  • ssRNA-5'
  • miRNA
  • All
Standard RNA Bases Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
(A,C,G,U) A,C,G,U $6.10 $7.75 $12.90 $17.00 $26.00
2'-Omethyl RNA Bases Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
2'-OMe RNA Bases (A, C, G, U) mA,mC,mG,mU $6.10 $7.75 $12.90 $17.00 $26.00
Standard DNA Bases Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
2'-Deoxy Bases (A, C, G, T) dA,dC, dG, dT $6.10 $7.75 $12.90 $17.00 $26.00
Base Modifications Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
1-Methyl-guanosine m1G $73.00 $80.00 $90.00 $115.00 $200.00
2,6-Diaminopurine DAP $90.00 $95.00 $105.00 $135.00 $230.00
2-Methyl-adenosine m2A $75.00 $93.00 $105.00 $130.00 $230.00
2-Aminopurine 2AP $75.00 $93.00 $105.00 $130.00 $230.00
4-Thio-uridine 4-S-U $100.00 $130.00 $145.00 $180.00 $320.00
5-Bromo-Uridine U[5Br] $73.00 $80.00 $90.00 $115.00 $200.00
5-Fluoro-cytidine C[5F] $73.00 $80.00 $90.00 $115.00 $200.00
5-Fluoro-uridine U[5F] $73.00 $80.00 $90.00 $115.00 $200.00
5-Iodo-uridine U[5I] $73.00 $80.00 $90.00 $115.00 $200.00
5-Methyl-cytidine 5-M-C $73.00 $80.00 $90.00 $115.00 $200.00
5-Methyl-Deoxycytidine 5-M-dC $73.00 $80.00 $90.00 $115.00 $200.00
5-Methyl-uridine rT $73.00 $80.00 $90.00 $115.00 $200.00
Inosine I $30.00 $32.00 $42.00 $58.00 $100.00
N2-Methyl-guanosine m2G $250.00 $350.00 $550.00 $900.00 $1600.00
N3-Methyl-uridine 3-M-U $73.00 $80.00 $90.00 $115.00 $200.00
N6,N6-Dimethyl-adenosine DMA $75.00 $93.00 $105.00 $130.00 $230.00
N6-Methyl-adenosine m6A $73.00 $80.00 $90.00 $115.00 $200.00
O6-Methyl-guanosine O6mG $85.00 $105.00 $125.00 $145.00 $270.00
Pseudouridine ~U $90.00 $95.00 $105.00 $135.00 $230.00
Purine ribonucleoside Pu $73.00 $80.00 $90.00 $115.00 $200.00
Pyrrolo-cytidine pC $90.00 $95.00 $105.00 $135.00 $230.00
Ribavirin RBV $73.00 $80.00 $90.00 $115.00 $200.00
Backbone modifications Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
Phosphorothioate * $8.00 $13.00 $15.00 $20.00 $29.00
Phosphorylation Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
5'-Phosphate 5'-P $45.00 $52.00 $63.00 $78.00 $135.00
2'-Modifications Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
2'-Amino-butyryl-pyrene-uridine 2'-P-U $100.00 $130.00 $145.00 $180.00 $320.00
2'-Amino-cytidine 2'-N-C $75.00 $93.00 $105.00 $130.00 $230.00
2'-Amino-uridine 2'-N-U $73.00 $80.00 $90.00 $115.00 $200.00
2'-Deoxy-uridine dU $30.00 $32.00 $42.00 $58.00 $100.00
2'-Fluoro-adenosine 2'-F-A $58.00 $60.00 $85.00 $87.00 $160.00
2'-Fluoro-cytidine 2'-F-C $40.00 $43.00 $57.00 $65.00 $100.00
2'-Fluoro-guanosine 2'-F-G $58.00 $60.00 $85.00 $87.00 $160.00
2'-Fluoro-uridine 2'-F-U $40.00 $43.00 $57.00 $65.00 $100.00
2'-OMe-inosine mI $73.00 $80.00 $90.00 $115.00 $200.00
Amino Modifiers Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
3'-Amino modifier C12 N12-3' $100.00 $130.00 $145.00 $180.00 $320.00
3'-Amino modifier C6 N6-3' $100.00 $130.00 $145.00 $180.00 $320.00
3'-Amino modifier C3 N3-3' $45.00 $52.00 $63.00 $78.00 $135.00
5'-Amino modifier C12 N12 $75.00 $93.00 $105.00 $130.00 $230.00
5'-Amino modifier C3 N3 $73.00 $80.00 $90.00 $115.00 $200.00
5'-Amino modifier C5 N5 $73.00 $80.00 $90.00 $115.00 $200.00
5'-Amino modifier C6 N6 $73.00 $80.00 $90.00 $115.00 $200.00
5-Aminohexylacrylamino-uridine 5-LC-N-U $100.00 $130.00 $145.00 $180.00 $320.00
Thiol Modifiers Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
3'-Disulfide thiol-modifier S-S-3' $100.00 $130.00 $145.00 $180.00 $320.00
5'-Disulfide thiol-modifier S-S $100.00 $130.00 $145.00 $180.00 $320.00
Spacer Modifiers Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
C18 Spacer 18S $30.00 $32.00 $42.00 $58.00 $100.00
C3 Spacer C3 $30.00 $32.00 $42.00 $58.00 $100.00
C9 Spacer 9S $30.00 $32.00 $42.00 $58.00 $100.00
dSpacer dab $75.00 $93.00 $105.00 $130.00 $230.00
rSpacer rab $75.00 $93.00 $105.00 $130.00 $230.00
Chain Terminators Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
3' Inverted abasic b $45.00 $52.00 $63.00 $78.00 $135.00
3' Inverted deoxy-thymidine idT-3' $45.00 $52.00 $63.00 $78.00 $135.00
3'-Terminal 3'-Deoxy-Guanosine 3'dG $55.00 $80.00 $90.00 $120.00 $180.00
3'-Terminal dideoxy-cytidine ddC $75.00 $93.00 $105.00 $130.00 $230.00
5' Inverted deoxy-thymidine idT $30.00 $32.00 $42.00 $58.00 $100.00
5' Terminal 5'-deoxy-ribo-adenosine 5'dA $30.00 $32.00 $42.00 $58.00 $100.00
5' Terminal 5'-deoxy-ribo-cytidine 5'dC $30.00 $32.00 $42.00 $58.00 $100.00
5' Terminal 5'-deoxy-ribo-guanosine 5'dG $30.00 $32.00 $42.00 $58.00 $100.00
5' Terminal 5'-deoxy-ribo-uridine 5'dU $30.00 $32.00 $42.00 $58.00 $100.00
Labeling Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
3-Biotin 3'-Bi $75.00 $95.00 $105.00 $130.00 $190.00
3'-Cholesterol 3'-Chl $110.00 $145.00 $165.00 $210.00 $365.00
3'-Cy3 Cy3-3' $85.00 $105.00 $125.00 $145.00 $270.00
3'-Cy5 Cy5-3' $85.00 $105.00 $125.00 $145.00 $270.00
3'-Cy5.5 Cy5^5-3' $85.00 $105.00 $125.00 $145.00 $270.00
3'-DY547 (Cy3 Alternative) DY547-3' $145.00 $160.00 $215.00 $250.00 $400.00
3'-Fluorescein 3'-Fl $75.00 $93.00 $105.00 $130.00 $230.00
3'-Biotin LC 3'-LCBi $110.00 $145.00 $165.00 $210.00 $365.00
3'-Biotin LC LC 3'-2LCBi $110.00 $145.00 $165.00 $210.00 $365.00
3'-Puromycin Pmn $45.00 $52.00 $63.00 $78.00 $135.00
3'-TAMRA 3'-TAM $165.00 $200.00 $240.00 $265.00 $460.00
5'-Biotin Bi $90.00 $95.00 $105.00 $155.00 $270.00
5'-Cholesterol Chl $110.00 $145.00 $165.00 $210.00 $365.00
5'-Cy3 Cy3 $75.00 $95.00 $115.00 $135.00 $250.00
5'-Cy5 Cy5 $75.00 $95.00 $115.00 $135.00 $250.00
5'-Cy5.5 Cy5^5 $75.00 $95.00 $115.00 $135.00 $250.00
5'-Dabcyl Dabcyl $100.00 $130.00 $145.00 $180.00 $320.00
5-DY547 (Cy3 Alternative) DY547 $125.00 $135.00 $150.00 $190.00 $325.00
5'-DY647 (Cy5 Alternative) DY647 $145.00 $160.00 $185.00 $270.00 $465.00
5'-DY677 (Cy5.5 Alternative) DY677 $200.00 $225.00 $245.00 $300.00 $500.00
5'-Fluorescein Fl $90.00 $95.00 $105.00 $135.00 $230.00
5'-Pyrene 5'-Pyr $115.00 $155.00 $190.00 $240.00 $460.00
5'-TAMRA TAM $165.00 $200.00 $240.00 $265.00 $460.00
5'-TET TET $75.00 $93.00 $105.00 $130.00 $230.00
Degenerate Bases Short Code 0.05 µmol 0.2 µmol 0.4 µmol 1.0 µmol 2.0 µmol
Pricing shown is for first degenerate base coupling, subsequent additions at standard base pricing
dN dN $45.00 $52.00 $63.00 $78.00 $135.00
dS dS $45.00 $52.00 $63.00 $78.00 $135.00
dW dW $45.00 $52.00 $63.00 $78.00 $135.00
mN mN $45.00 $52.00 $63.00 $78.00 $135.00
rN rN $45.00 $52.00 $63.00 $78.00 $135.00
rS rS $45.00 $52.00 $63.00 $78.00 $135.00
rW rW $45.00 $52.00 $63.00 $78.00 $135.00