EGFR S768I Reference Standard, FFPE, 50%
Horizon FFPE Reference standards are cell-line derived making them reproducible, renewable, and affordable experimental controls for molecular diagnostic assays. They are formulated to mimic patient samples and serve as excellent quality controls by acting as performance indicators for the whole diagnostic workflow.
Horizon FFPE standards eliminate the variability associated with patient-derived reference standards, and avoid the hassle of sourcing, characterizing, and documenting your own cell line mixes. Using a proprietary method of mild fixation and homogenous paraffin embedding, we generate highly reproducible and consistent FFPE curls. Our standards yield high molecular weight DNA which can be analyzed in a wide-range of assays including qPCR, Sanger sequencing and next-generation sequencing.
Product Description: EGFR S768I Reference Standard, FFPE, 50%
Catalog number: HD707
Amino Acid Change: S768I
Nucleotide change: c.2303G>T
Variant Allele Frequency: 50%
Cosmic Genomic Mutation ID: COSV51768106
Cosmic Legacy ID: COSM6241
GRCh38 position: 7:55181312
Unit Size: 15 µm section
Fixation Method: 4% PFA (w/v)
Expected DNA Yield: ≥ 400ng Using Maxwell RSC Plus FFPE DNA Extraction kit
Expiry: See all product shelf-life information
Cell Line Background: RKO
Exome Sequencing Data: Download additional sequencing data from the parental cell
Genotype and Allelic Frequency: Droplet Digital PCRTM
DNA integrity: Agarose gel electrophoresis
Manufacturing Quality: ISO 13485:2016
Use: Research Use Only
Cell Line Characterization
Chromatograph showing heterozygosity for the EGFR S768I mutation within EGFR
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