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Mimix™ Genome in a Bottle Ashkenazim PGP Son, FFPE Reference Standard

Horizon has harnessed its’ proprietary FFPE processing capabilities to generate ‘Well Characterized Genome’ (WCG) FFPE samples, in collaboration with the Genome in a Bottle Consortium (GIAB). These standards are ideal for NGS workflows, especially the validation and development of whole-genome sequencing protocols.

DISCONTINUATION NOTE: GM24149 has been discontinued and replaced by two products developed in collaboration with MDIC using the GM24385 cell line – please see Mimix™ Geni™ Onco Mix 1 DNA/RNA FFPE (HD852) and Negative FFPE (HD876) reference standards. For any further queries, please contact us.

Horizon FFPE Reference standards are cell-line derived making them reproducible, renewable, and affordable experimental controls for molecular diagnostic assays. They are formulated to mimic patient samples and serve as excellent quality controls by acting as performance indicators for the whole diagnostic workflow.

 

Technical Information

Horizon FFPE standards eliminate the variability associated with patient-derived reference standards, and avoid the hassle of sourcing, characterizing, and documenting your own cell line mixes. Using a proprietary method of mild fixation and homogenous paraffin embedding, we generate highly reproducible and consistent FFPE curls. Our standards yield high molecular weight DNA which can be analyzed in a wide-range of assays including qPCR, Sanger sequencing and next-generation sequencing.

 

Product Information

Product Description: Genome in a Bottle Ashkenazim PGP Son Reference Standard

Catalog number: GM24385

Gene: Full genome

Format: FFPE

Unit Size:10 FFPE sections (15 µm sections)

Fixation Method: 4% PFA (w/v)

Expected DNA Yield: ≥ 400ng Using Maxwell RSC Plus FFPE DNA Extraction kit

Storage: 4°C

Shipping: Ambient

Expiry: See all product shelf-life information

 

Quality Control

Genotype and Allelic Frequency: Droplet Digital PCRTM

DNA integrity: Agarose gel electrophoresis

Quantification: Quantifluor™

Manufacturing Quality: ISO 13485:2016

Intended use: For assay developers and molecular diagnostic labs for routine performance monitoring of molecular biology assays. Research use only. Not for diagnostic procedures.