Demonstration of a repeatable pooled lentiviral sgRNA screen in primary human T cells
Gene editing by CRISPR has led to significant advances in immunotherapy development. Here we offer several tips for successful editing in T cells, including recommendations for cell handling, nucleofection, and analysis.
CRISPRテクノロジーによりゲノム編集細胞集団を作製後、クローン細胞株を用いるかプール細胞集団を用いるかを決定する際に考慮すべき最も重要な4つの事項をご説明しています。
Examples of studies using siRNAs targeting lncRNAs to inspire your next experiment.
Quality control (QC) is vital for Next-generation sequencing (NGS). Here we discuss best practices that will save you time, money, and headaches.
Technology from Horizon Discovery has been awarded Top Innovation of the Year by The Scientist Magazine for the past seven consecutive years.
Enzymatically synthesized guide RNA can trigger unwanted cellular responses
Interested in prime editing? Learn about this new technique and how Horizon's customizable long oligo synthesis can help get you started.
Achieve DNA-free guaranteed gene editing with synthetic predesigned sgRNA reagents and libraries covering the entire human genome.
Performing RNAi with a shRNA vector is often a straightforward and well documented approach to gene knockdown.