COVID-19 impacts us all in unexpected ways - If you're still in the lab or working at home please let us know how we can help - Contact Us

In regards to custom cell line engineering, can the antibiotic resistance be removed at a later date?

Absolutely. All selection markers are flanked by LoxP sites allowing cre-mediated excision to be used to remove the marker leaving only a single LoxP site (34 bp) as a scar. This step could be performed either by the researcher when necessary or as a subsequent project by Horizon.