Edit-R™ gene editing reagents
Guaranteed to edit your target gene
Algorithm designed to maximize functional protein knockout and minimize off-target effects
Gene editing refers to the process of changing regions of cellular DNA. The most common gene editing techniques involve inactivating a gene’s function (knockout), introducing or correcting a SNP mutation, or adding a reporter tag to an endogenous gene (knock-in). These changes are permanent and heritable, resulting in a newly engineered cell line.
With our Edit-R™ CRISPR-Cas9 reagents, researchers can make targeted, specific edits to any gene in practically any cell type. Additionally, Horizon offers a wide selection of pre-made edited cell lines and expert genome engineering services.
With our Edit-R™ CRISPR-Cas9 reagents, researchers can make targeted, specific edits to any gene in practically any cell type. Additionally, Horizon offers a wide selection of pre-made edited cell lines and expert genome engineering services.
Engineered cell models
Ready-to-go or tailored to individual needs
Knockout, knock-in, reporter and SNP lines available - relevant cell models, specific to any application
CRISPR-Cas9 genome editing overview
App note: CRISPR knockout in iPSCs
Highly specific and efficient gene knockdown
See how Edit-R reagents are used to generate functional protein knockouts in human induced pluripotent stem cells.
Gene editing workflow guide
Planning a gene knockout or knock-in?
This workflow guide will assist you in selecting the best Edit-R genome engineering tools for your application.
CRISPR screening libraries
Accelerate functional genomic screens with CRISPR libraries
Available custom designed or pre-defined in pooled and arrayed formats.
CRISPR & Cas9 All-in-one vector!
Single-transfection solution for a simplified workflow
Express both Cas9 nuclease and a gene specific guide RNA with your choice of fluorescent reporter or antibiotic resistance for easy selection.
Knock-in your edit
Create a SNP or knock-in a reporter gene
Design templates for precise genomic insertion using the HDR pathway.
CRISPR Design Tool
Algorithm guided custom CRISPR guide RNA design.
Design guide RNA for use in over 40 species or with any nuclease.
Edit-R™ guarantee
Peace of mind that your editing experiment will be successful
All predesigned guide RNAs are fully guaranteed to edit the target gene, ensuring the highest likelihood of a successful knockout experiment.