Modify an existing microRNA mimic or inhibitor, target a novel microRNA, or request an Accell™ microRNA inhibitor or stabilized mimic for special applications.

Custom microRNA

Use our online ordering tool to easily enter your mature microRNA and have our proprietary miRIDIAN mimic modification pattern applied to you sequence.

Multiple scales and processing options are available, as well as a wide variety of 5’ and 3’ modifications. Watch our step-by-step video tutorial to learn how to use the custom miRNA ordering tool. 


Alternatively, if you would prefer a custom generated quote fill out the custom synthesis quote form.

Additional microRNA modulation tools are available by Scientific Support quote

If you are looking for a standard miRIDIAN microRNA Mimic or Hairpin Inhibitor for a human, mouse, or rat microRNA and you do not require any additional modifications or special processing, use the search function in the upper right-hand corner of the page to find pre-designed microRNA modulation tools.

For custom inhibitors, Accell inhibitors and stabilized mimics, please request a quote online or contact Scientific Support.

For Custom miRIDIAN microRNA mimics order using our online tool.

Extended options for enhancing your microRNA mimic or inhibitor

  • Stabilized Mimics: Add stabilizing modifications to a miRIDIAN Mimic for additional stability in nuclease-rich environments
  • Accell Inhibitors: Add Accell modifications to a microRNA inhibitor for delivery into cells without a transfection reagent

Advantages of custom synthesis

  • Target a microRNA in an alternative species
  • Introduce mismatches to study microRNA biomechanics
  • Select In vivo processing and large-scale synthesis for animal studies
  • Apply a wide range of chemical modifications 

Application notes

Featured articles

Product & technical manuals

Product inserts

Product selection guides


Recommended Reading

  • Dharmacon publications
    These publications are from Dharmacon scientists highlighting internal research and collaborations in the fields of CRISPR-Cas9, RNAi, et al.
  • RNAi screening references
    Selected publications of general interest to researchers performing RNAi (siRNA, shRNA, microRNA) libraries for functional genomic screening.
  • Understanding RNAi off-target effects
    The articles in this document are recommended to assist in understanding mechanisms, sources, and strategies to reduce off-targets in RNAi experiments.

Safety Data Sheets