These tools are for ordering antisense oligos (ASOs) between 15-35 nucleotides in length, for oligos outside this range use these links to order custom RNA or custom DNA.
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Order individual ASOs
Custom synthesis of 15-35 bases at either 0.05 μmol or 1.0 μmol scale, with the option of HPLC purification.
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Order multiple ASOs
Use this online tool to order multiple custom ASOs with the same characteristics (scale, purification and modifications).
Rely on Dharmacon’s 20+ years of oligo synthesis expertise for your ASO needs.
Our tool supports multiple modifications patterns to enhance the stability & binding affinity of the oligo, including phosphorothioate linkages, 2’-O-methyl, locked nucleic acids, and MOE (methoxyethyl) modifications. We also offer flexibility in synthesis scale and purification options to meet your experimental requirements. Learn more about antisense oligos (ASOs) on our application page.
For more details on Revvity's continued compliance with the United States Framework For Nucleic Acid Synthesis Screening, please see our self-attestation.
We offer a wide selection of chemical modifications, including a variety of fluorophores and functional groups. These can be applied to single-strand RNA, DNA, RNA-DNA chimeras, siRNA, ASO, and microRNA oligos. Modifications available on our web ordering tools can be found at our Bases and Modifications page.
NOTE: Many other modifications are available upon request. The online ordering tools only include a subset of common modifications. For assistance please contact Scientific Support.
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Synthesis scale does not represent final yield. Length, modifications and processing options will result in decreased oligo yield. Purification is strongly recommended for modified RNA requests. Please contact scientific support for more information on yield estimates or recommended processing for your specific needs.