Accelerate your gene editing experiments with "CRISPR-ready" stable Cas9-expressing cell lines

Choose from a range of popular cell backgrounds, available for both Cas9 (CRISPR knockout) and dCas9-VPR (CRISPR activation) so you can complete gain- and loss-of-function studies in the same background.

  • Reduce the time it takes to determine gene function - no need to generate your own Cas9 cell line.
  • Reduce the cost of your individual experiments - no need to add a nuclease.
  • Simply transfect gene specific synthetic guide RNA for CRISPR knockout or CRISPR activation

All cell lines are QC validated for Cas9 or dCas9-VPR functionality

Cas9 cell lines

Simplify gene editing experiments with stably expressing Cas9 cell lines

dCas9-VPR cell lines

Streamline gene activation experiments with stably expressing dCas9-VPR cell lines

Order all your gene editing reagents

Cas9 stable cell lines are optimized to work with with Edit-R pre-designed sgRNA products and DharmaFECT transfection reagents.

Edit-R sgRNA products

Browse the full range of Edit-R predesigned synthetic sgRNA products

DharmaFECT transfection reagents

For efficient siRNA & CRISPR guide RNA delivery Optimized solutions for RNA transfection into a wide range of cell types for successful gene editing experiments.
Already have a knock-out target in mind?

Our collection of knock-out cell lines are trusted by academia, biotech, and pharma and suitable for almost any application: from TIDVAL to antibody validation.

Knock-out cell lines

Accelerate your discovery with thousands of knock-out cell lines in the near-haploid background HAP1