The world's largest oncology reference standard with companion in silico data set


Have confidence in your cancer assay

Optimize your validation or monitor assay performance with OncoSpan

Take advantage of a renewable, reproducible, and highly characterized reference control material providing consistency from assay development to routine monitoring.

  • Highly multiplexed reference control panel containing over 370 variants across 152 oncogenes, including >27 indels
  • Cell line derived control material is commutable to patient samples
  • Develop, troubleshoot and assess bioinformatics performance with a companion high coverage, batch specific in silico NGS data set
  • Available as cell-free DNA, FFPE curls, and genomic DNA
  • Range of allele frequencies enable rapid determination of LOD in your assay and sensitivities
  • Demonstrated repeatability and reproducibility with an R2 correlation coefficient in NGS ranging from 0.95 to 0.97 for all OncoSpan formats


OncoSpan applications
  • Enable novel cancer assay development
  • Conduct routine monitoring of assay performance and data analysis
Utilize NGS controls to calibrate your assays
  • Improve patient selection for clinical trials
  • Develop early cancer detection methods
  • Assess therapeutic efficacy

Choose your OncoSpan format

OncoSpan cfDNA

Cell-free DNA in buffer or alternate plasma for use in liquid biopsies

OncoSpan FFPE

Cells embedded in FFPE slides for use in extraction and assay control


Latest OncoSpan resources

Application Note - Digging deeper into OncoSpan's NGS data

  Here we explore deep sequencing information provided with the OncoSpan product range

How to get the most out of your NGS data with OncoSpan

In this blog article we explore how to investigate false calling and downstream applications