Can I use the Edit-R SAM tracrRNA with your Cas9 reagents?

No. Because of the added MS2 aptamer sequence, Edit-R SAM tracrRNA is specifically designed for use in activation experiments with cells expressing the SAM components dCas9-VP64 and MS2-p65-HSF1. If Cas9 reagents are required, we recommend using our Edit-R dCas9-VPR reagents with the standard Edit-R tracrRNA (Cat# U-002005-XX) for synthetic crRNA: tracrRNA experiments.