Do your lentiviral vectors encode the VPX gene?
The Gag-Pro packaging component of our packaging system encodes vpr not vpx. Vpr is functionally similar to vpx. Vpx is found in HIV-2. Our vector is based on HIV-1. The vpx/vpr gene is encoded only in the Gag-Pro packaging component of the packaging system used to create lentiviral particles with our lentiviral vectors. The gene is not encoded on the lentiviral transfer vector itself.