There are no delays on our products or support as a result of COVID-19. If there is a way we can assist you, we are here to help - Contact us

Do all off-target genes respond to the ON-TARGETplus modification pattern?

No. However, analysis shows that most of the non-responsive off-target genes are found to have high complementarily in their seed region. For the ON-TARGETplus predesigned siRNAs we have combined seed region frequency analysis with the ON-TARGETplus modification AND pooling to minimize off-target effects.