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What is the stability of siRNA?

A duplex of RNA is significantly more resistant to nucleases than a single strand. However, maintaining sterile, RNAse free conditions is always recommended as a precaution. Dried pellets are stable at room temperature for 2-4 weeks, but should be placed at -20�C or -80�C for long term storage. Under these conditions, a dried siRNA will be stable for at least one year.