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BioProduction Congress - Mammalian and Microbial Biopharmaceutical Manufacturing

This event was held at the Convention Centre in Dublin, Ireland and played host to 400+ experts from some of the leading global biopharma companies.

Jamie Freeman, Bioproduction Product Manager at Horizon Discovery gave a talk on 17 October from 12:20 on 'Engineering the Next Generation of CHO Cells'.

Aside from single gene knockouts to allow for metabolic selection systems, the CHO host itself remains largely unchanged from that which was used thirty years ago. Jamie presented how we have used a combination of techniques including genome engineering approaches such as CRISPR and rAAV to improve the biomanufacturing capacity of our manufacturing ready GS knockout CHO K1 cell line.