siSTABLE Cyclophilin B Control siRNA is a validated positive control, guaranteed to silence cyclophilin B in human cells. This control siRNA is chemically modified to significantly extend siRNA stability and is recommended for use as a positive control in experiments using siSTABLE-modified siRNA against a target gene or where increased stability of the siRNA is desired.
Also known as peptidylprolyl isomerase B (PPIB), cyclophilin B is associated with the secretory pathway. This gene is abundantly expressed in most cells, and because it is non-essential, knockdown of the corresponding mRNA does not affect cell viability. Targets accession number NM_000942.
- Experimentally validated for consistent, potent silencing of cyclophilin B in human cells
- Chemically modified to significantly extend siRNA stability
- Suitable for use in experimental settings with high nuclease activity
Stability of siSTABLE siRNA in 100% Human Serum
Potent Silencing by siSTABLE Cyclophilin B siRNA