Immune cell based assay screens

Fully compatible with any CRISPR & RNAi screening project

Cytotoxicity assays

Find out whether the therapeutic enhances the immune system's ability to find and kill target cancer cells using:

  • Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) assays
  • Complement-Dependent Cytotoxicity (CDC) assays
  • Antibody-dependent cell mediated phagocytosis assays
  • T cell mediated tumor cell lysis assays

Immune suppression assays

Assess your therapeutic's ability to relieve suppression of T cells using Myeloid-Derived Suppressor Cells (MDSC).

Also, we can employ Treg suppression assays to analyze the therapeutic's ability to either enhance or repress Treg suppression on T cells.

T cell proliferation assays

Rapid identification of agents that modulate antigen presenting cell (APC)-mediated T cell activation with:

  • MLR (mixed lymphocyte reactions) assays
  • T cell activation assays

RNA-based immune cell screens

Gene editing and screening service in primary human immune cells.

Answer clinically relevant biological questions in relevant cell types.

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