Functional genomic screening

From target selection to patient stratification.
Identify and characterize therapeutic targets and biomarkers.

Arrayed genomic screening service

Get quality screening results, right the first time.

Using synthetic crRNA and siRNA reagents on a one-gene per well basis with complex assay readouts.

Pooled genomic screening service

Dedicated team for each pooled screening project.

Employing lentiviral CRISPRko/i/a approaches in highly multiplexed pooled screens.

Screening libraries

Have flexibility: Select from catalog CRISPR and RNAi libraries or create custom libraries in pooled and arrayed formats.

Ensuring library specificity with algorithm optimized guide RNA.

RNA-based immune cell screens

Gene editing service for primary human immune cells.

Address clinically relevant biological questions in vitro.

Webinar - CRISPR screening from target selection to patient stratification

Video - Gene modulation technologies in the development of cell based therapies

Learn about the principles, strategies and experimental outcomes of CRISPR screening     

Application note - Dual CRISPRi/a screens

Read about CRISPR screens for:

  • Drug mechanisms of action
  • Target identification and validation

Application note - pooled phenotypic CRISPR screens

Read more about pooled CRISPR–Cas9 knock-out screens - valuable tools for new drug target identification

CRISPR knockout screening

Custom services for unique research projects.

Probe gene function. Find drug targets. Stratify patients.

CRISPRi screening

Open up new research opportunities with CRISPR interference screens - CRISPRi!

CRISPRa screening

Study gain of gene function with CRISPR activation.

Dual CRISPRi/a screening

Exploit the power of paired loss-of-function and gain-of-function screening.

Use of parallel CRISPRi and CRISPRa gene modulation to identify drug interactions with paired gene perturbation analysis.

siRNA screening

Benefit from rapid and efficient workflows.

Expanding your gene modulation options.

Functional genomic screening with CRISPR technologies

Learn about CRISPR screening and techniques

Review article

Read a recent insightful review article headlining in SLAS Discovery's March issue entitled 'CRISPR: A Screener's Guide'.

CRISPR screens in primary human T cells

Gain a better understanding of how immune cells function using functional genomic screens.