RNA-based immune cell screens

Gene editing services for primary human immune cells.

Address clinically relevant biological questions in vitro.

Pooled and arrayed T-cell screen services

Elucidate critical genes for T cell functionality and interactions

  • Choose from a variety of validated readouts and assays
  • Select from focused to broad gene sets
  • Achieve robust and reliable gene knockout results

Arrayed B-cell screens

From modulating tumor responses to studying autoimmune disease.

  • Edit stimulated B cells and analyze which gene(s) can affect B cell functionality
  • Use viable and potent edited cells for complex functional assays with other immune cells

 

Immune cell-based assays

Evaluate therapeutic efficacy in relevant immune cell-base environments using assays for:

  • Cytotoxicity
  • Immune suppression
  • T cell proliferation

CRISPR edited immune cells service available.

Functional genomic screening services

From target selection to patient stratification.
Identify and characterize therapeutic targets and biomarkers.

CRISPR and RNAi specialists!

What we deliver

  • Consultation with specialist team
  • Summary screen aims
  • Key findings & conclusions
  • Tables and graph of key data metrics
  • Data reports include raw data, quality metrics, and analyzed data with hit calling

Article: Explore how primary cells are now used in CRISPR screens

To find more out, read an insightful Nature article entitled:

'The primary CRISPR directive - the next frontier in cell screening'