Alzheimers Disease AD

Horizon has generated the first knockout rats of Apolipoprotein E, as well as the first knockin of humanized ApoE4. ApoE has been demonstrated to play an important role in the development of Alzheimer’s disease (AD), and these unique models will be instrumental in further unravelling the role of ApoE and ApoE4 in the pathology of AD.

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Alzheimer's Animal Models

Animal models for Alzheimer's Disease:




hApoE4 KI

Alzheimer's brochure