siSTABLE Non-Targeting siRNA #1 was designed to have a minimum of four mismatches to all human, mouse, and rat genes to avoid non-specific silencing due to off-targets. This negative control siRNA is chemically modified to significantly extend siRNA stability an is recommended for use as a negative control in experiments using siSTABLE modified siRNA against a target gene or where increased stability of the control is desired.
- BLAST analysis confirms at least 4 mismatches with all known human, mouse, and rat genes
- Chemically modified to significantly extend siRNA stability
- Recommended for use as a non-specific control in experiments using siSTABLE modified siRNA against the target gene or where increased stability of the control is desired
siRNA-mediated RNAi experiments should include non-targeting siRNA as a control for non-sequence-specific effects. Changes in mRNA or protein levels in cells or tissues treated with these controls reflect a non-specific baseline cellular response to which the levels in cells or tissues treated with target-specific siRNA can be compared.
To request a larger quantity or in vivo processing of this control product, please contact Technical Support.
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|Storage Conditions||-20 C|
|Stability at Recommended Storage Conditions||At least 12 months|
Stability of siSTABLE siRNA in 100% Human Serum