Dual CRISPRi and CRISPRa Screening
Exploit the power of paired loss-of-function and gain-of-function screening
The Dual Screen uses parallel CRISPRi and CRISPRa gene modulation technologies and provides the ability to identify drug-gene interactions through paired gene perturbation analysis. The approach offers researchers a novel, powerful and systematic way to:
- Explore drug mechanisms of action
- Identify novel biomarkers
- Identify new combination therapy targets
- De-orphan and reposition drugs for new therapeutic applications
Download the complete application note:
By using CRISPRi and CRISPRa together you can power up your drug discovery and development programs and accelerate your target discovery. The Dual Screen is the new gold-standard in drug-gene interaction screening; providing deep insight into the biological effects of down- and up-regulating genes in parallel in the same experimental model.
Learn more about our Dual CRISPRi & CRISPRa screening platforms and the benefits of dual screening:
Watch our webinar - Next generation target discovery: systematic application of the CRISPR toolkit:
Find out more about our Dual CRISPRi & CRISPRa sceening service and how it can give you insight into complex gene networks and drug responses:
Also explore our research reagents for CRISPRa.
Contact us for more information on Dual CRISPRi & CRISPRa