CRISPR-Cas9 gene editing workflows
Choose the right Edit-R tools for your application
Leveraging a naturally occurring form of immunity found in archaea and bacteria, short RNAs can be used to guide nuclease proteins to gene targets within complex eukaryotic genomes with high specificity. Popularly known as CRISPR-Cas (Clustered Regularly Interspersed Short Palindromic Repeats) technology, these systems rely upon CRISPR-associated (Cas) proteins and have the potential to carry out genome editing functions or alter gene expression. The components of CRISPR-Cas9 genome editing systems can be combined in multiple ways for various gene editing applications.
We offer a wide selection of pre-designed and custom CRISPR-Cas9 gene editing tools and formats. Our new applications-based selection guide for gene editing will help you quickly and easily determine the best option for your particular needs. Whether your goal is gene knockout from imperfect repair by non-homologous end joining (NHEJ) or creating an insertion or other knockin with homology-directed repair (HDR); whether you wish to investigate entire gene families or biological pathways, or just a small set of genes, this workflow guide will assist you in selecting the right Edit-R genome engineering tools for your application.