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A breakthrough aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout

This literature review delves into an application of gene editing that diverges from the conventional paradigm. Rather than introducing mutations through sequential or multiple DSBs, this method achieves simultaneous gene knock-in and knockout in a single engineering step.

Disclaimer: The Pin-point™ base editing platform technology is available for clinical or diagnostic study and commercialization under a commercial license from Revvity with further development from the licensee.

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