Immune cell based assay screens

Fully compatible with any CRISPR & RNAi screening project

Cytotoxicity assays

Find out whether the therapeutic enhances the immune system's ability to find and kill target cancer cells using:

  • Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) assays
  • Complement-Dependent Cytotoxicity (CDC) assays
  • Antibody-dependent cell mediated phagocytosis assays
  • T cell mediated tumor cell lysis assays

Immune suppression assays

Assess your therapeutic's ability to relieve suppression of T cells using Myeloid-Derived Suppressor Cells (MDSC).

Also, we can employ Treg suppression assays to analyze the therapeutic's ability to either enhance or repress Treg suppression on T cells.

T cell proliferation assays

Rapid identification of agents that modulate antigen presenting cell (APC)-mediated T cell activation with:

  • MLR (mixed lymphocyte reactions) assays
  • T cell activation assays

RNA-based immune cell screens

Gene editing and screening service in primary human immune cells.

Answer clinically relevant biological questions in relevant cell types.

Combine with apoptosis assays

Rapidly screen agents on their capacity of inducing cell apoptosis in a broad panel of cell types.

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