siGLO Cyclophilin B Control siRNA
Correlate fluorescence uptake and silencing activity with a single control
A stable, fluorescent positive control suitable for RNAi experiments in human, mouse, or rat cells. Silences the Cyclophilin B gene and is labeled with Cy3.
siGLO Cyclophilin B Control siRNA is a validated positive control, guaranteed to silence cyclophilin B in human, mouse, or rat cells. This control siRNA is chemically modified to significantly extend siRNA stability and fluorescence compared to conventional siRNAs similarly labeled with fluorophores.
Also known as peptidylprolyl isomerase B (PPIB), cyclophilin B is associated with the secretory pathway. This gene is abundantly expressed in most cells, and because it is non-essential, knockdown of the corresponding mRNA does not affect cell viability.
Highlights
- Targets accession numbers NM_000942 (Human), NM_011149 (Mouse), or NM_022536 (Rat)
- Labeled with Cy3
- Absorbance/Emission Max is 547/563 nm
- A Cy3, Rhodamine or PE filter can be used
- Significantly extended intensity of the fluorescence signal (7 days or longer)
- Positive correlation of fluorescence with transfection efficiency and target gene silencing
To request a larger quantity or in vivo processing of this control product, please email Scientific Support.
