licensing terms

CHO K1 (GS Null) Licensing

We will not charge royalties or milestones

Our innovative and flexible licensing structure ensures that access to this high-performance cell line platform is not cost prohibitive and is accessible to companies of all sizes. We achieve this by  providing different structures that best meet your short and long term aspirations, including an option to undertake an evaluation of the platform for a limited period.

CHO SOURCE platform

The CHO SOURCE platform provides a kit to enable rapid identification of clones expressing high levels of recombinant therapeutic protein during your stable cell line development process, consisting of:

1 vial of 10x106 cGMP GS null CHO K1 cells;

A Glutamine Synthetase plasmid vector for selection of product-expressing clones;

Methods and protocols;

Documentation tracing the origin and derivation of the GS null CHO K1 cells, including  adventitious agents testing results

This Glutamine Synthetase null CHO K1 expression system generates high titre biomanufacturing cell lines without the need of MSX or Methotrexate additives after selection. By using the GS selection system there is no requirement for lengthy amplification steps commonly used in alternative systems such as DHFR selection.

To discuss your cell line needs and to find out how we can meet them, please contact us.