Cell line-derived reference standards to verify research workflows
Closely mimicking patient samples
Following our transition from Horizon Discovery to Revvity, we’ve renamed our cell line-derived reference standards as Mimix Reference Standards.
There are no changes to any of our cell line-derived reference standards products or services – just a new name that reflects how our controls provide a closer representation of patient samples to test and verify new assays and sequencing workflows.
Mimix Reference Standards are cell line-derived to maintain genomic complexity and mimic patient material across the molecular diagnostics workflow. Our reference standards are platform-agnostic for implementation into quality control workflows and can be compatible across a range of platforms including Next Generation Sequencing, droplet-digital and Real-Time PCR, and Sanger sequencing.
We work to support our customers in verifying that their molecular assays and workflows are performing as expected by offering:
- A wide range of off-the-shelf products in multiple formats and allelic frequencies for end-to-end process control; including gDNA, FFPE, ctDNA and formalin-compromised DNA formats
- In-house engineering to develop custom controls, allowing researchers to select almost any gene of interest
- Cell line-derived reference standards to closely mimic patient samples
- A reliable and renewable source of materials
- Products developed and manufactured under ISO 13485:2016 and ISO 9001:2015
- Custom solutions available from our in-house cell line engineering experts
Read our latest resources
View our brochure to see the cell line-derived Mimix product range and product types available.
View our brochure
Why using cell line-derived reference material is critical for reliable genetic testing in oncology.
Download Whitepaper
This technical note investigates how different methods for quantifying our gDNA and ctDNA reference standards can yield varying results.
Download Application Note
For research use only. Not for use in diagnostic procedures.
Analysis techniques
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Latest products
Quantitative Multiplex - Moderate FFPE
Revvity Mimix™ Quantitative Multiplex Moderate FFPE reference standard is a biologically relevant quality control material for assessing the performance of molecular biology assays that detect somatic mutations, such as qPCR, ddPCR, Sanger sequencing and NGS.
Genomic DNA - Male
This Mimix™ gDNA reference standard is biologically relevant quality control material which can be used to assess the performance and consistency of various molecular biology assays such as qPCR, ddPCR, Sanger sequencing and NGS.
PTEN Loss FFPE
Consistent and reliable cell-line based reference material replicating PTEN loss in FFPE format
Lymphoid Cancer Panel FFPE
FFPE version of our popular Lymphoid gDNA panel (HD840). This cell line derived reference material can be used for end-to-end validation of molecular assays designed for testing lymphoid malignancies from FFPE samples.
Non-invasive prenatal testing (NIPT)
As the awareness of the potential of Non-Invasive Prenatal Testing (NIPT) grows in the clinical context worldwide, there is a need to systematically ensure that the results are consistent and precise. Revvity’s new array of reference standards will enable to assess the accuracy of NIPT tests
Colorectal Cancer Panel FFPE
This Colorectal Cancer Panel FFPE Reference Standard mimics patient samples and can be used for end-to-end validation of molecular assays designed for testing colorectal cancer specific mutations.
Prostate Cancer Panel FFPE
This reference material resembling clinical (FFPE) samples can be used for end-to-end validation of molecular assays designed for testing prostate cancer specific mutations.
Pan-cancer & large panel controls
OncoSpan
Providing a comprehensive oncology reference standard with over 370 variants across 152 genes.
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