Cell Lines For Studying Solute Carrier (SLC) Gene

Solute carriers overview 

Solute carriers are the second largest group of membrane proteins. Current estimates are that there are almost 400 members which can be divided into 52 families.

They can participate in two main forms of transportation:

  • Facilitative or passive, where solutes flow with their electrochemical gradient
  • Secondary active transporters, which allow solutes to move against their electrochemical gradient through coupling to a second solute flowing with its gradient.

Solute Carrier Diagram

Due to the diverse nature of the solutes carried by this large family of proteins they are implicated in a wide variety of processes from neurosignalling, nucleoside synthesis and salvage to transportation drugs.

Ready-to-go cell models

There are over 7,500 cell models available ready-to-go. Choose from the HAP1 cell line or cancer-relevant cell backgrounds. 

Find the cell model relevant for your research by searching for your gene of interest. 

Browse cell models

Examples of popular knockouts

MTCH1

SLC25A18

SLC30A1

SLC39A8

SLC11A2

SLC25A20

SLC30A3

SLC39A9

SLC12A4

SLC25A22

SLC30A5

SLC41A3

SLC12A5

SLC25A25

SLC30A7

SLC43A1

SLC12A6

SLC25A29

SLC31A1

SLC43A2

SLC12A7

SLC25A3

SLC33A1

SLC43A3

SLC12A9

SLC25A30

SLC34A2

SLC44A1

SLC16A10

SLC25A32

SLC35A1

SLC46A3

SLC16A13

SLC25A37

SLC35A3

SLC4A10

SLC16A3

SLC25A38

SLC35A5

SLC4A2

SLC17A5

SLC25A4

SLC35C1

SLC4A8

SLC17A9

SLC25A40

SLC35E2B

SLC52A2

SLC19A1

SLC25A46

SLC35F2

SLC5A4

SLC1A4

SLC25A5

SLC36A4

SLC5A6

SLC1A5

SLC25A6

SLC37A4

SLC7A1

SLC20A2

SLC26A2

SLC38A10

SLC7A3

SLC22A18

SLC27A1

SLC38A2

SLC7A6

SLC22A5

SLC27A2

SLC38A5

SLC9A3R1

SLC25A1

SLC27A3

SLC38A9

SLC9A3R2

SLC25A10

SLC27A4

SLC39A1

SLC9A7

SLC25A11

SLC29A1

SLC39A14

SLC9C1

SLC25A13

SLC29A4

SLC39A3

UCP1

SLC25A15

SLC2A8

SLC39A6